ACTA1 isoform is the major component in skeletal muscle thin filament of sarcomere and is essential for force production, muscle contraction and movement [13, 14]. of overexpressed PAX3-FOXO1 protein. CCG-1423 is an inhibitor of RhoA-MKL1-SRF signaling, we observed there was a synergistic effect between this inhibitor and to suppress reporter … Continue reading ACTA1 isoform is the major component in skeletal muscle thin filament of sarcomere and is essential for force production, muscle contraction and movement [13, 14]